Safe Call Now

Thursday, June 23, 2016

Pharamacogenetics & the #1stresponder

Safe Call Now Partner Dr. Michael Genovese


As first responders do we know anything about medication when it is prescribed to us from our doctors?  The side effects, if it will actually work or not?  This is great information you need to know for your health and wellness.  Stay safe out there!!!

Michael V. Genovese, M.D., J.D.
Chief Medical Officer – Sierra Tucson 

With the advancement of medicine and the multitude of available options, psychiatrists face numerous challenges in tailoring the appropriate course of individualized treatment for patients. Pharmacogenomics is the study of how a person’s individual DNA affects his or her response to medications and a scientific method of evaluating which medications a patient is likely to tolerate. The primary role of pharmacogenomics is to develop rational means to optimize drug therapy, with respect to the patient’s genotype, to ensure maximum efficacy with minimal adverse effects.

There are many factors involved in the decision making process of administering medication such as efficacy, side effect profile, compliance, cost, family history, and the patient’s previous medication trials. Approximately 50% of patients do not respond to their initial medication treatment and up to 30% discontinue due to intolerable side effects. Additionally, nearly 70% of patients are non-adherent to their prescribed medication schedule, with adverse reactions representing the most common cause. The statistics reveal the demand for an individualized approach to patient care and a treatment plan specific to the patient’s needs.

Saturday, June 11, 2016

Change... I Don't Like It, or Do I?

Safe Call Now President and Founder Sean Riley


As we enter into summer and the changing of the seasons once again it got me wondering about “change” and how it impacts us.  Change can be scary, fun, exciting and terrifying all at the same time.  Do any of us like to change?  I propose to you… if we don’t embrace change, we don’t grow personally.  Change is something I’m not a big fan of but it is mandatory if I want to become the person who I want to be.  Genuine, loving, self-reliant and all those characteristics I admire.

I made the big geographical move one year ago.  After 25 years living in one place I packed up and moved 300 miles to the east (still near a large airport of course) to a city I’ve never lived in before.  I learned to dance in the rain all of those years and as my life has grown and I’ve seen the world out there, it is time to learn more about life and experience all it can bring.

When I was in my addiction I was the preverbal “people pleaser” as I never wanted to confront issues or upset the balance of my life.  I wanted everything to just stay “status quo” and not hurt anyone’s feelings or my own.  By doing so all I did was compromise my self-esteem to make others happy.  I sacrificed myself for the benefit of others.  I thought this was noble as I put others first.  You know the old saying when you’re in an airplane…  You can’t help others put on the oxygen mask until you put yours on first!!!